Basic Information
ID: ALA3536667
Type: ADME
Description: Inhibition of human KMO assessed as 3-hydroxykynurenine formation preincubated for 5 mins using 100 uM kynurenine as substrate by LC-MS/MS analysis in presence of 3 mg/ml plasma protein
Format: BAO_0000357
Organism: Homo sapiens
Tissue: Plasma
Target: Kynurenine 3-monooxygenase(ALA2145)
Document: ALA3526063
Inhibition of human KMO assessed as 3-hydroxykynurenine formation preincubated for 5 mins using 100 uM kynurenine as substrate by LC-MS/MS analysis in presence of 3 mg/ml plasma protein: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3536667
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 421.46 | 3.54 | 3.54 |