ID: ALA3536997
Type: ADME
Description: Prodrug conversion assessed as human recombinant CYP1A2-mediated (Z)-N'-hydroxy-6-(5-(5-((Z)-N'-methoxycarbamimidoyl)pyridin-2-yl)furan-2-yl) nicotinimidamide formation at 5 uM after 180 mins incubation by HPLC-UV chromatogram
Format: BAO_0000357
Organism: Homo sapiens
Target: Cytochrome P450 1A2(ALA3356)
Document: ALA3525966
Prodrug conversion assessed as human recombinant CYP1A2-mediated (Z)-N'-hydroxy-6-(5-(5-((Z)-N'-methoxycarbamimidoyl)pyridin-2-yl)furan-2-yl) nicotinimidamide formation at 5 uM after 180 mins incubation by HPLC-UV chromatogram: 1
Bioactivity
Activity Types for Assay ALA3536997
Drug metabolism
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
402.84 | 1.94 | 1.94 |