Basic Information
ID: ALA3537290
Type: ADME
Description: Unbound drug partitioning coefficient, Kp of the compound assessed as ratio of unbound concentration in Sprague-Dawley rat brain to unbound concentration in plasma
Organism: Rattus norvegicus
Strain: Sprague-Dawley
Tissue: Plasma
Activity Charts
Bioactivity
Activity Types for Assay ALA3537290
Kp
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 357.79 | 3.93 | 3.93 |
| 319.34 | 1.27 | 1.27 |
| 284.75 | 3.15 | 3.15 |
| 267.37 | 1.61 | 1.61 |
| 249.35 | 2.15 | 2.15 |
| 454.61 | 5.09 | 5.09 |
| 398.40 | 3.70 | 3.70 |
| 266.34 | 0.45 | 0.45 |
| 138.12 | 1.09 | 1.09 |
| 259.35 | 2.58 | 2.58 |
| 252.35 | 0.60 | 0.60 |
| 242.34 | 1.35 | 1.35 |
| 444.49 | -0.14 | -0.14 |
| 130.25 | 1.88 | 1.88 |
| 370.59 | 5.89 | 5.89 |
| 285.34 | 1.20 | 1.20 |
| 299.37 | 1.50 | 1.50 |
| 853.92 | 3.74 | 3.74 |
| 248.33 | 1.91 | 1.91 |
| 198.27 | 2.70 | 2.70 |
| 265.35 | 1.99 | 1.99 |
| 223.30 | 1.94 | 1.94 |
| 670.86 | 3.09 | 3.09 |
| 567.80 | 4.75 | 4.75 |
| 456.57 | 2.72 | 2.72 |
| 277.41 | 4.17 | 4.17 |
| 267.24 | -0.20 | -0.20 |
| 230.10 | 2.36 | 2.36 |
| 325.77 | 4.32 | 4.32 |
| 315.37 | 1.05 | 1.05 |
| 255.36 | 3.35 | 3.35 |
| 151.25 | 1.91 | 1.91 |
| 308.77 | 3.58 | 3.58 |
| 296.15 | 4.36 | 4.36 |
| 213.66 | 1.86 | 1.86 |
| 256.10 | 2.01 | 2.01 |
| 454.45 | 0.27 | 0.27 |
| 477.05 | 5.09 | 5.09 |
| 239.75 | 3.30 | 3.30 |
| 171.24 | 1.37 | 1.37 |
| 301.34 | 0.75 | 0.75 |
| 170.24 | 2.18 | 2.18 |
| 520.48 | -1.13 | -1.13 |
| 324.42 | 3.17 | 3.17 |
| 324.42 | 3.17 | 3.17 |
| 461.47 | -1.24 | -1.24 |
| 461.47 | -0.89 | -0.89 |
| 332.31 | 3.97 | 3.97 |
| 822.95 | 4.34 | 4.34 |
| 339.37 | -0.40 | -0.40 |
| 129.17 | -1.03 | -1.03 |
| 309.41 | 0.63 | 0.63 |
| 263.38 | 2.63 | 2.63 |
| 206.25 | 0.39 | 0.39 |
| 339.46 | 3.32 | 3.32 |
| 740.76 | 1.54 | 1.54 |