Prodrug conversion assessed as human recombinant CYP4F2-mediated (Z)-N'-hydroxy-6-(5-(5-((Z)-N'-methoxycarbamimidoyl)pyridin-2-yl)furan-2-yl) nicotini...

Basic Information

ID: ALA3537358

Type: ADME

Description: Prodrug conversion assessed as human recombinant CYP4F2-mediated (Z)-N'-hydroxy-6-(5-(5-((Z)-N'-methoxycarbamimidoyl)pyridin-2-yl)furan-2-yl) nicotinimidamide formation at 5 uM after 180 mins incubation by HPLC-UV chromatogram

Format: BAO_0000357

Organism: Homo sapiens

Target:  Cytochrome P450 4F2(ALA3379)

Document:  ALA3525966

Prodrug conversion assessed as human recombinant CYP4F2-mediated (Z)-N'-hydroxy-6-(5-(5-((Z)-N'-methoxycarbamimidoyl)pyridin-2-yl)furan-2-yl) nicotinimidamide formation at 5 uM after 180 mins incubation by HPLC-UV chromatogram: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
402.841.941.94