Prodrug conversion assessed as human recombinant CYP1A2-mediated (3Z,3'Z)-6,6'-(furan-2,5-diyl)bis(N'-hydroxynicotinimidamide) formation at 5 uM after...

Basic Information

ID: ALA3537359

Type: ADME

Description: Prodrug conversion assessed as human recombinant CYP1A2-mediated (3Z,3'Z)-6,6'-(furan-2,5-diyl)bis(N'-hydroxynicotinimidamide) formation at 5 uM after 180 mins incubation by HPLC-UV chromatogram

Format: BAO_0000357

Organism: Homo sapiens

Target: Cytochrome P450 1A2(ALA3356)

Document: ALA3525966

Prodrug conversion assessed as human recombinant CYP1A2-mediated (3Z,3'Z)-6,6'-(furan-2,5-diyl)bis(N'-hydroxynicotinimidamide) formation at 5 uM after 180 mins incubation by HPLC-UV chromatogram: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA3537359

Drug metabolism

Total(1)

Parent Molecular Weight	ALogP	Polar Surface Area
402.84	1.94	1.94

Parent Molecular Weight

ALogP

Polar Surface Area

402.84

1.94

Prodrug conversion assessed as human recombinant CYP1A2-mediated (3Z,3'Z)-6,6'-(furan-2,5-diyl)bis(N'-hydroxynicotinimidamide) formation at 5 uM after...

Basic Information

Activity Charts

Compound Summary