Prodrug conversion assessed as rat recombinant CYP2D2-mediated (Z)-N'-hydroxy-6-(5-(5-((Z)-N'-methoxycarbamimidoyl)pyridin-2-yl)furan-2-yl) nicotinimi...

ID: ALA3537363

Type: ADME

Description: Prodrug conversion assessed as rat recombinant CYP2D2-mediated (Z)-N'-hydroxy-6-(5-(5-((Z)-N'-methoxycarbamimidoyl)pyridin-2-yl)furan-2-yl) nicotinimidamide formation at 5 uM after 180 mins incubation by HPLC-UV chromatogram

Format: BAO_0000357

Organism: Rattus norvegicus

Target:  Cytochrome P450 2D2(ALA2483)

Document:  ALA3525966

Prodrug conversion assessed as rat recombinant CYP2D2-mediated (Z)-N'-hydroxy-6-(5-(5-((Z)-N'-methoxycarbamimidoyl)pyridin-2-yl)furan-2-yl) nicotinimidamide formation at 5 uM after 180 mins incubation by HPLC-UV chromatogram: 1