Basic Information
ID: ALA3537396
Type: ADME
Description: Inhibition of mouse OAT1 expressed in CHO cells assessed as inhibition of fluorescein uptake at 500 uM over 20 mins relative to untreated-control
Organism: Mus musculus
Cell type: CHO
Activity Charts
Bioactivity
Activity Types for Assay ALA3537396
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 334.40 | 0.86 | 0.86 |
| 380.42 | 0.95 | 0.95 |
| 350.40 | 0.70 | 0.70 |
| 396.45 | 0.59 | 0.59 |
| 367.81 | 0.62 | 0.62 |
| 517.56 | -0.24 | -0.24 |
| 401.44 | 1.90 | 1.90 |
| 435.44 | -1.17 | -1.17 |
| 546.59 | -1.30 | -1.30 |
| 435.89 | 2.55 | 2.55 |
| 470.33 | 3.20 | 3.20 |
| 285.37 | 2.20 | 2.20 |
| 427.46 | 0.10 | 0.10 |
| 378.41 | 0.49 | 0.49 |
| 349.41 | 0.32 | 0.32 |
| 424.39 | -0.54 | -0.54 |
| 523.57 | 0.98 | 0.98 |
| 414.48 | 2.48 | 2.48 |
| 384.44 | 0.55 | 0.55 |
| 461.50 | 0.09 | 0.09 |
| 363.39 | 0.15 | 0.15 |
| 645.68 | -1.11 | -1.11 |
| 347.40 | 0.44 | 0.44 |
| 455.47 | -0.62 | -0.62 |
| 471.55 | -0.73 | -0.73 |
| 216.26 | -0.54 | -0.54 |
| 532.56 | -1.89 | -1.89 |