Basic Information
ID: ALA3537619
Type: ADME
Description: Activation of PXR in rat hepatocytes assessed as increase in CYP3A-mediated testosterone 6beta-hydroxylation at 10 uM after 24 hrs by HPLC analysis relative to control
Format: BAO_0000219
Organism: Rattus norvegicus
Cell type: Hepatocyte
Target: Nuclear receptor subfamily 1 group I member 2(ALA2146315)
Document: ALA3526076
Activation of PXR in rat hepatocytes assessed as increase in CYP3A-mediated testosterone 6beta-hydroxylation at 10 uM after 24 hrs by HPLC analysis relative to control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3537619
FC
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 392.47 | 1.90 | 1.90 |