Drug metabolism assessed as recombinant CYP2C8 (unknown origin)-mediated 2-(5-chloro-4-(2-(2-chloro-4-cyclopropylphenylsulfonamido)-4-(1-hydroxy-2-met...

Basic Information

ID: ALA3537742

Type: ADME

Description: Drug metabolism assessed as recombinant CYP2C8 (unknown origin)-mediated 2-(5-chloro-4-(2-(2-chloro-4-cyclopropylphenylsulfonamido)-4-(1-hydroxy-2-methylpropan-2-ylcarbamoyl)phenoxy)-2-fluorophenyl)acetic acid formation at 10 uM after 30 mins by LC-MS/MS analysis

Format: BAO_0000357

Organism: Homo sapiens

Target:  Cytochrome P450 2C8(ALA3721)

Document:  ALA3526017

Drug metabolism assessed as recombinant CYP2C8 (unknown origin)-mediated 2-(5-chloro-4-(2-(2-chloro-4-cyclopropylphenylsulfonamido)-4-(1-hydroxy-2-methylpropan-2-ylcarbamoyl)phenoxy)-2-fluorophenyl)acetic acid formation at 10 uM after 30 mins by LC-MS/MS analysis: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
609.506.766.76