Drug metabolism assessed as recombinant CYP2C8 (unknown origin)-mediated 2-(4-(4-(tert-butylcarbamoyl)-2-(2-chloro-4-(1-hydroxycyclopropyl)phenylsulfo...

Basic Information

ID: ALA3537750

Type: ADME

Description: Drug metabolism assessed as recombinant CYP2C8 (unknown origin)-mediated 2-(4-(4-(tert-butylcarbamoyl)-2-(2-chloro-4-(1-hydroxycyclopropyl)phenylsulfonamido)phenoxy)-5-chloro-2-fluorophenyl)acetic acid formation at 10 uM after 30 mins by LC-MS/MS analysis

Format: BAO_0000357

Organism: Homo sapiens

Target:  Cytochrome P450 2C8(ALA3721)

Document:  ALA3526017

Drug metabolism assessed as recombinant CYP2C8 (unknown origin)-mediated 2-(4-(4-(tert-butylcarbamoyl)-2-(2-chloro-4-(1-hydroxycyclopropyl)phenylsulfonamido)phenoxy)-5-chloro-2-fluorophenyl)acetic acid formation at 10 uM after 30 mins by LC-MS/MS analysis: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
609.506.766.76