Basic Information
ID: ALA3538473
Type: ADME
Description: Activity of recombinant human CYP3A4 expressed in Escherichia coli JM109 co-expressing P450 reductase assessed as enzyme-mediated drug metabolism treated with LBH589 measured after 1 hr by LC-MS analysis in presence of cytochrome b5
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3538473
Drug metabolism
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 365.43 | 2.44 | 2.44 |
| 349.43 | 2.42 | 2.42 |
| 350.42 | 3.02 | 3.02 |
| 333.44 | 3.31 | 3.31 |
| 334.42 | 3.91 | 3.91 |