Assay Report Card

Basic Information

ID: ALA3538858

Type: ADME

Description: Drug metabolism in human liver cytosol at 20 uM assessed as (1R,2S,5S)-N-((2S,3R)-4-amino-1-cyclobutyl-3-hydroxy-4-oxobutan-2-yl)-3-((S)-2-(3-tert-butylureido)-3,3-dimethylbutanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide formation at 20 uM after 60 mins in presence of pre-incubation with ritonavir by LC-MS/MS/FSA method

Organism: Homo sapiens

Tissue: Liver

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
519.691.711.71