ID: ALA3538861
Type: ADME
Description: Drug metabolism in human liver cytosol at 20 uM assessed as (1R,2S,5S)-N-((2R,3R)-4-amino-1-cyclobutyl-3-hydroxy-4-oxobutan-2-yl)-3-((S)-2-(3-tert-butylureido)-3,3-dimethylbutanoyl)-6,6-dimethyl-3-azabicyclo[3.1.0]hexane-2-carboxamide formation at 20 uM after 60 mins in presence of AKR inhibitor ibuprofen by LC-MS/MS/FSA method
Organism: Homo sapiens
Tissue: Liver
Bioactivity
Activity Types for Assay ALA3538861
Compound recovery
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
519.69 | 1.71 | 1.71 |