Basic Information
ID: ALA3539185
Type: ADME
Description: Activity of human CYP3A5 expressed in microsomes isolated from baculovirus infected insect cell assessed as enzyme-mediated 3-(4-((6-methoxy-1-methyl-1H-benzo[d]imidazol-2-yl)methoxy)phenyl)-2-(methylsulfonyl)propanamide formation at 20 uM after 2 hrs by radio-HPLC/LC-MS/MS analysis in presence of NADPH-generating system/SAM
Organism: Homo sapiens
Subcellular Fraction: Microsomes
Activity Charts
Bioactivity
Activity Types for Assay ALA3539185
Drug metabolism
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 435.91 | 3.06 | 3.06 |