Basic Information
ID: ALA3539253
Type: ADME
Description: Activity of human recombinant FMO3 expressed in microsomes isolated from baculovirus infected insect BTI-TN-5B1-4 cells assessed as enzyme-mediated 3-(2,4-dimethylphenylthio)-4-(piperazin-1-yl)phenol formation at 8 to 50 uM after 120 mins by HPLC/MS-MS analysis in presence of NADPH regenerating system with NADP+
Organism: Homo sapiens
Cell type: BTI-TN-5B1-4
Subcellular Fraction: Microsomes
Activity Charts
Bioactivity
Activity Types for Assay ALA3539253
Drug metabolism
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 379.37 | 3.86 | 3.86 |