Drug metabolism in phenotyped human liver microsomes assessed as formation of 4-(2-(2,4-dimethylphenylthio)phenyl)piperazin-1-ol at 8 to 50 uM after 6...

Basic Information

ID: ALA3539257

Type: ADME

Description: Drug metabolism in phenotyped human liver microsomes assessed as formation of 4-(2-(2,4-dimethylphenylthio)phenyl)piperazin-1-ol at 8 to 50 uM after 60 mins by HPLC/MS-MS analysis in presence of NADPH regenerating system with NADP+

Format: BAO_0000019

Organism: Homo sapiens

Tissue: Liver

Target:  Liver microsome(ALA2367379)

Document:  ALA3525899

Drug metabolism in phenotyped human liver microsomes assessed as formation of 4-(2-(2,4-dimethylphenylthio)phenyl)piperazin-1-ol at 8 to 50 uM after 60 mins by HPLC/MS-MS analysis in presence of NADPH regenerating system with NADP+: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
379.373.863.86