ID: ALA3539567
Type: ADME
Description: Activity of human recombinant FMO3 expressed in microsomes isolated from baculovirus infected insect BTI-TN-5B1-4 cells assessed as enzyme-mediated 3-methyl-4-(2-(piperazin-1-yl)phenylthio)benzoic acid formation at 8 to 50 uM after 120 mins by HPLC/MS-MS analysis in presence of NADPH regenerating system with NADP+
Organism: Homo sapiens
Cell type: BTI-TN-5B1-4
Subcellular Fraction: Microsomes
Bioactivity
Activity Types for Assay ALA3539567
Drug metabolism
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
379.37 | 3.86 | 3.86 |