Activity of human recombinant FMO3 expressed in microsomes isolated from baculovirus infected insect BTI-TN-5B1-4 cells assessed as enzyme-mediated 3-...

ID: ALA3539567

Type: ADME

Description: Activity of human recombinant FMO3 expressed in microsomes isolated from baculovirus infected insect BTI-TN-5B1-4 cells assessed as enzyme-mediated 3-methyl-4-(2-(piperazin-1-yl)phenylthio)benzoic acid formation at 8 to 50 uM after 120 mins by HPLC/MS-MS analysis in presence of NADPH regenerating system with NADP+

Format: BAO_0000219

Organism: Homo sapiens

Cell type: BTI-TN-5B1-4

Subcellular Fraction: Microsomes

Target:  Dimethylaniline monooxygenase [N-oxide-forming] 3(ALA3430864)

Document:  ALA3525899

Activity of human recombinant FMO3 expressed in microsomes isolated from baculovirus infected insect BTI-TN-5B1-4 cells assessed as enzyme-mediated 3-methyl-4-(2-(piperazin-1-yl)phenylthio)benzoic acid formation at 8 to 50 uM after 120 mins by HPLC/MS-MS analysis in presence of NADPH regenerating system with NADP+: 1