Basic Information
ID: ALA3540101
Type: ADME
Description: Drug metabolism in human liver microsomes assessed as monoclonal antibody-mediated inhibition of CYP2A6-mediated (R)-1-(4-(4-fluoro-2-(hydroxymethyl)-1H-indol-5-yloxy)-5-methylpyrrolo[1,2-f][1,2,4]triazin-6-yloxy)propan-2-ol formation at 2 and 20 uM for 30 mins by LC/MS analysis
Format: BAO_0000019
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsomes
Target: Cytochrome P450 2A6(ALA5282)
Document: ALA3526086
Drug metabolism in human liver microsomes assessed as monoclonal antibody-mediated inhibition of CYP2A6-mediated (R)-1-(4-(4-fluoro-2-(hydroxymethyl)-1H-indol-5-yloxy)-5-methylpyrrolo[1,2-f][1,2,4]triazin-6-yloxy)propan-2-ol formation at 2 and 20 uM for 30 mins by LC/MS analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3540101
Drug metabolism
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 370.38 | 3.52 | 3.52 |