Basic Information
ID: ALA3540148
Type: ADME
Description: Activity of human recombinant CYP2D6 expressed in microsomes isolated from human AHH-1 cells assessed as enzyme-mediated 3-methyl-4-(2-(piperazin-1-yl)phenylthio)benzoic acid formation at 8 to 50 uM after 120 mins by HPLC/MS-MS analysis in presence of NADPH regenerating system with NADP+
Organism: Homo sapiens
Cell type: AHH-1
Subcellular Fraction: Microsomes
Activity Charts
Bioactivity
Activity Types for Assay ALA3540148
Drug metabolism
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 379.37 | 3.86 | 3.86 |