Basic Information
ID: ALA3540149
Type: ADME
Description: Activity of human recombinant CYP3A4 expressed in microsomes isolated from human AHH-1 cells assessed as enzyme-mediated 1-(2-(2,4-dimethylphenylsulfinyl)phenyl)piperazine formation at 8 to 50 uM after 120 mins by HPLC/MS-MS analysis in presence of NADPH regenerating system with NADP+
Organism: Homo sapiens
Cell type: AHH-1
Subcellular Fraction: Microsomes
Activity Charts
Bioactivity
Activity Types for Assay ALA3540149
Drug metabolism
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 379.37 | 3.86 | 3.86 |