Basic Information
ID: ALA3540237
Type: ADME
Description: Drug metabolism assessed as human recombinant UGT1A10-mediated (2S,3S,4S,5R,6S)-6-(2-(4-(4-(tert-butylcarbamoyl)-2-(2-chloro-4-cyclopropylphenylsulfonamido)phenoxy)-5-chloro-2-fluorophenyl)acetoxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid formation at 10 uM after 30 mins by LC-MS/MS analysis
Format: BAO_0000357
Organism: Homo sapiens
Target: UDP-glucuronosyltransferase 1-10(ALA1743320)
Document: ALA3526017
Drug metabolism assessed as human recombinant UGT1A10-mediated (2S,3S,4S,5R,6S)-6-(2-(4-(4-(tert-butylcarbamoyl)-2-(2-chloro-4-cyclopropylphenylsulfonamido)phenoxy)-5-chloro-2-fluorophenyl)acetoxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylic acid formation at 10 uM after 30 mins by LC-MS/MS analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3540237
Drug metabolism
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 609.50 | 6.76 | 6.76 |