Assay Report Card

Basic Information

ID: ALA3540345

Type: ADME

Description: Drug level in Sprague-Dawley rat plasma assessed as compound formation treated with [14C]brivanib alaninate at 100 mg/kg, po administered as single dose via gavage measured after 2 hrs by HPLC analysis

Organism: Rattus norvegicus

Strain: Sprague-Dawley

Tissue: Plasma

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
370.383.523.52
312.303.463.46
488.431.031.03
466.452.532.53
392.372.942.94
400.372.912.91
386.382.702.70
422.352.332.33
450.453.353.35
370.343.223.22