Basic Information
ID: ALA3540356
Type: ADME
Description: Drug uptake in Sprague-Dawley rat plasma treated with [14C]brivanib alaninate assessed as AUC (0 to 6 hrs) of total radio activity at 100 mg/kg, po administered as single oral dose by HPLC analysis
Organism: Rattus norvegicus
Strain: Sprague-Dawley
Tissue: Plasma
Activity Charts
Bioactivity
Activity Types for Assay ALA3540356
AUC metabolite/AUC radiolabel
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 370.38 | 3.52 | 3.52 |
| 466.45 | 2.53 | 2.53 |
| 392.37 | 2.94 | 2.94 |
| 400.37 | 2.91 | 2.91 |
| 422.35 | 2.33 | 2.33 |
| 450.45 | 3.35 | 3.35 |