Basic Information
ID: ALA3540574
Type: Binding
Description: Inhibition of Sprague-Dawley rat Bsep expressed in plasma membrane vesicles of Sf21 cells assessed as inhibition of ATP-dependent [3H]taurocholate uptake
Organism: Rattus norvegicus
Strain: Sprague-Dawley
Cell type: Sf21
Activity Charts
Bioactivity
Activity Types for Assay ALA3540574
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 303.29 | 1.77 | 1.77 |
| 441.55 | 4.37 | 4.37 |
| 341.43 | 0.56 | 0.56 |
| 138.12 | 1.09 | 1.09 |
| 259.35 | 2.58 | 2.58 |
| 266.34 | 1.38 | 1.38 |
| 211.26 | 1.13 | 1.13 |
| 330.75 | 1.89 | 1.89 |
| 326.83 | 3.72 | 3.72 |
| 385.51 | 2.09 | 2.09 |
| 211.22 | 0.44 | 0.44 |
| 153.18 | 0.60 | 0.60 |
| 137.14 | -0.31 | -0.31 |
| 494.01 | 3.64 | 3.64 |
| 318.87 | 4.89 | 4.89 |
| 468.37 | 2.11 | 2.11 |
| 276.75 | 1.74 | 1.74 |
| 236.30 | 2.73 | 2.73 |
| 275.35 | 1.77 | 1.77 |
| 198.27 | 2.70 | 2.70 |
| 379.50 | 4.36 | 4.36 |
| 214.05 | 1.16 | 1.16 |
| 206.28 | 3.07 | 3.07 |
| 309.43 | 4.01 | 4.01 |
| 236.27 | 3.39 | 3.39 |
| 144.21 | 2.29 | 2.29 |
| 238.33 | 2.85 | 2.85 |
| 151.16 | 1.35 | 1.35 |
| 356.42 | 4.37 | 4.37 |
| 238.16 | 0.07 | 0.07 |
| 356.45 | 3.16 | 3.16 |
| 357.44 | 2.49 | 2.49 |
| 470.02 | 3.55 | 3.55 |
| 159.23 | 1.75 | 1.75 |
| 102.09 | -1.62 | -1.62 |
| 199.16 | -1.10 | -1.10 |
| 270.35 | 1.78 | 1.78 |
| 454.45 | 0.27 | 0.27 |
| 190.21 | -0.96 | -0.96 |
| 276.21 | 3.21 | 3.21 |
| 361.83 | 3.55 | 3.55 |
| 263.79 | 3.96 | 3.96 |
| 1202.63 | ||
| 435.89 | 2.55 | 2.55 |
| 470.33 | 3.20 | 3.20 |
| 285.37 | 2.20 | 2.20 |
| 337.46 | -0.77 | -0.77 |
| 404.34 | 5.50 | 5.50 |
| 551.63 | 4.20 | 4.20 |
| 270.21 | 3.25 | 3.25 |
| 312.41 | 2.53 | 2.53 |
| 248.31 | 1.68 | 1.68 |
| 365.41 | 0.02 | 0.02 |
| 238.24 | 0.96 | 0.96 |
| 179.22 | 0.72 | 0.72 |
| 118.16 | -0.22 | -0.22 |
| 326.44 | 5.17 | 5.17 |
| 245.33 | 2.35 | 2.35 |
| 301.73 | 4.34 | 4.34 |
| 372.81 | 3.14 | 3.14 |
| 249.27 | 3.60 | 3.60 |
| 531.44 | 4.21 | 4.21 |
| 273.24 | 2.55 | 2.55 |
| 169.18 | 0.08 | 0.08 |
| 581.58 | -8.16 | -8.16 |
| 323.42 | 1.63 | 1.63 |
| 822.95 | 4.34 | 4.34 |
| 392.47 | 1.90 | 1.90 |
| 225.21 | -1.33 | -1.33 |
| 149.21 | 0.11 | 0.11 |
| 453.88 | 2.69 | 2.69 |
| 516.72 | 5.67 | 5.67 |
| 697.78 | 4.75 | 4.75 |
| 346.34 | 2.18 | 2.18 |
| 114.17 | 0.71 | 0.71 |
| 277.27 | 1.15 | 1.15 |
| 372.09 | -1.27 | -1.27 |
| 289.16 | 3.59 | 3.59 |
| 466.98 | 4.10 | 4.10 |
| 376.42 | 2.35 | 2.35 |
| 261.39 | 2.71 | 2.71 |
| 314.41 | 1.46 | 1.46 |
| 253.71 | 3.09 | 3.09 |
| 1056.40 | 2.75 | 2.75 |
| 740.76 | 1.54 | 1.54 |