Activity of human CYP2C8 expressed in microsomes isolated from baculovirus infected insect cell assessed as enzyme-mediated 2-mercapto-3-(4-((6-methox...

Basic Information

ID: ALA3540842

Type: ADME

Description: Activity of human CYP2C8 expressed in microsomes isolated from baculovirus infected insect cell assessed as enzyme-mediated 2-mercapto-3-(4-((6-methoxy-1-methyl-1H-benzo[d]imidazol-2-yl)methoxy)phenyl)propanoic acid formation at 20 uM after 2 hrs by radio-HPLC/LC-MS/MS analysis in presence of NADPH-generating system

Format: BAO_0000019

Organism: Homo sapiens

Subcellular Fraction: Microsomes

Target:  Cytochrome P450 2C8(ALA3721)

Document:  ALA3526048

Activity of human CYP2C8 expressed in microsomes isolated from baculovirus infected insect cell assessed as enzyme-mediated 2-mercapto-3-(4-((6-methoxy-1-methyl-1H-benzo[d]imidazol-2-yl)methoxy)phenyl)propanoic acid formation at 20 uM after 2 hrs by radio-HPLC/LC-MS/MS analysis in presence of NADPH-generating system: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
435.913.063.06