Basic Information
ID: ALA3541009
Type: ADME
Description: Activity of human CYP2C8 expressed in microsomes isolated from baculovirus infected insect cell assessed as enzyme-mediated compound formation treated with [14C]-rivoglitazone at 20 uM after 2 hrs by radio-HPLC/LC-MS/MS analysis in presence of NADPH-generating system and NADPH-generating system/SAM
Format: BAO_0000019
Organism: Homo sapiens
Subcellular Fraction: Microsomes
Target: Cytochrome P450 2C8(ALA3721)
Document: ALA3526048
Activity of human CYP2C8 expressed in microsomes isolated from baculovirus infected insect cell assessed as enzyme-mediated compound formation treated with [14C]-rivoglitazone at 20 uM after 2 hrs by radio-HPLC/LC-MS/MS analysis in presence of NADPH-generating system and NADPH-generating system/SAM: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3541009
Drug metabolism
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 383.43 | 2.75 | 2.75 |
| 355.39 | 1.55 | 1.55 |
| 371.46 | 2.49 | 2.49 |
| 413.46 | 2.38 | 2.38 |
| 383.43 | 3.04 | 3.04 |