Basic Information
ID: ALA3541098
Type: ADME
Description: Inhibition of CYP1A2 in human liver microsomes using phenacetin substrate by LC-MS/MS method
Format: BAO_0000019
Organism: Homo sapiens
Tissue: Liver
Subcellular Fraction: Microsomes
Target: Cytochrome P450 1A2(ALA3356)
Document: ALA3526101
Inhibition of CYP1A2 in human liver microsomes using phenacetin substrate by LC-MS/MS method: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3541098
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 319.34 | 1.27 | 1.27 |
| 267.37 | 1.61 | 1.61 |
| 454.61 | 5.09 | 5.09 |
| 326.83 | 3.72 | 3.72 |
| 375.87 | 4.43 | 4.43 |
| 318.87 | 4.89 | 4.89 |
| 403.98 | 3.94 | 3.94 |
| 355.87 | 5.18 | 5.18 |
| 404.50 | 5.39 | 5.39 |
| 306.24 | 5.18 | 5.18 |
| 263.79 | 3.96 | 3.96 |
| 495.64 | 5.27 | 5.27 |
| 554.59 | -1.20 | -1.20 |
| 366.55 | 4.83 | 4.83 |
| 514.63 | 7.26 | 7.26 |
| 418.45 | 2.97 | 2.97 |
| 424.09 | 5.46 | 5.46 |
| 394.44 | 0.62 | 0.62 |
| 479.53 | 3.68 | 3.68 |
| 346.34 | 2.18 | 2.18 |