Basic Information
ID: ALA3541357
Type: ADME
Description: Activity of human UGT1A3 expressed in microsomes isolated from baculovirus infected insect cell assessed as enzyme-mediated compound formation treated with [14C]-rivoglitazone at 20 uM after 4 hrs by radio-HPLC/LC-MS/MS analysis in presence of NADPH-generating system/SAM
Format: BAO_0000019
Organism: Homo sapiens
Subcellular Fraction: Microsomes
Target: UDP-glucuronosyltransferase 1-3(ALA3542435)
Document: ALA3526048
Activity of human UGT1A3 expressed in microsomes isolated from baculovirus infected insect cell assessed as enzyme-mediated compound formation treated with [14C]-rivoglitazone at 20 uM after 4 hrs by radio-HPLC/LC-MS/MS analysis in presence of NADPH-generating system/SAM: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3541357
Drug metabolism
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 591.60 | 0.49 | 0.49 |
| 573.58 | 0.66 | 0.66 |