Basic Information
ID: ALA3541842
Type: ADME
Description: Activity of human CYP3A4 expressed in microsomes isolated from baculovirus infected insect cell assessed as enzyme-mediated 2-hydroxy-3-(4-((6-methoxy-1-methyl-1H-benzo[d]imidazol-2-yl)methoxy)phenyl)propanamide formation at 20 uM after 2 hrs by radio-HPLC/LC-MS/MS analysis in presence of NADPH-generating system and NADPH-generating system/SAM
Format: BAO_0000019
Organism: Homo sapiens
Subcellular Fraction: Microsomes
Target: Cytochrome P450 3A4(ALA340)
Document: ALA3526048
Activity of human CYP3A4 expressed in microsomes isolated from baculovirus infected insect cell assessed as enzyme-mediated 2-hydroxy-3-(4-((6-methoxy-1-methyl-1H-benzo[d]imidazol-2-yl)methoxy)phenyl)propanamide formation at 20 uM after 2 hrs by radio-HPLC/LC-MS/MS analysis in presence of NADPH-generating system and NADPH-generating system/SAM: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3541842
Drug metabolism
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 435.91 | 3.06 | 3.06 |