Basic Information
ID: ALA3542045
Type: ADME
Description: Efflux ratio of permeability from apical to basolateral over basolateral to apical side in P-gp knockdown human Caco2 cells at 10 uM up to 120 mins by reverse-phase liquid chromatography with triple-quadrupole tandem mass spectrometry analysis relative to vector transfected cells
Format: BAO_0000219
Organism: Homo sapiens
Cell type: Caco-2
Target: ADMET(ALA612558)
Document: ALA3525968
Efflux ratio of permeability from apical to basolateral over basolateral to apical side in P-gp knockdown human Caco2 cells at 10 uM up to 120 mins by reverse-phase liquid chromatography with triple-quadrupole tandem mass spectrometry analysis relative to vector transfected cells: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3542045
Ratio
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 350.44 | 3.29 | 3.29 |
| 780.95 | 2.22 | 2.22 |