Basic Information
ID: ALA3562054
Type: Functional
Description: PubChem BioAssay. A cell based assay for assessing THP-1 cell cytotoxicity of Inhibitors Targeting HIV-1 Vif-dependent Degradation of Human APOBEC3G. (Class of assay: confirmatory)
Cell type: THP-1
Activity Charts
Bioactivity
Activity Types for Assay ALA3562054
CC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 172.23 | 1.81 | 1.81 |
| 160.22 | 1.67 | 1.67 |
| 454.45 | 0.27 | 0.27 |
| 506.47 | 2.32 | 2.32 |
| 302.37 | 4.20 | 4.20 |
| 174.25 | 2.08 | 2.08 |
| 228.25 | 2.97 | 2.97 |
| 282.30 | 2.23 | 2.23 |
| 544.53 | 6.81 | 6.81 |
| 307.35 | 4.02 | 4.02 |
| 911.15 | 9.03 | 9.03 |
| 240.22 | 3.40 | 3.40 |
| 309.42 | 3.61 | 3.61 |
| 317.28 | 3.80 | 3.80 |
| 412.44 | 3.96 | 3.96 |
| 518.47 | 4.60 | 4.60 |
| 330.29 | 1.53 | 1.53 |
| 374.28 | 3.41 | 3.41 |
| 295.37 | 3.70 | 3.70 |
| 453.50 | 3.20 | 3.20 |
| 318.18 | 3.25 | 3.25 |
| 226.75 | 2.65 | 2.65 |
| 319.38 | 2.17 | 2.17 |
| 432.40 | 4.19 | 4.19 |
| 229.24 | 2.55 | 2.55 |
| 290.75 | 1.76 | 1.76 |
| 329.36 | 4.73 | 4.73 |
| 544.99 | -0.35 | -0.35 |
| 302.28 | 1.72 | 1.72 |
| 321.80 | 2.85 | 2.85 |
| 361.35 | 1.13 | 1.13 |
| 572.57 | 4.11 | 4.11 |
| 390.46 | 4.35 | 4.35 |
| 335.41 | 2.47 | 2.47 |
| 355.83 | 4.41 | 4.41 |
| 404.49 | 3.29 | 3.29 |
| 369.76 | 3.27 | 3.27 |
| 333.58 | 4.54 | 4.54 |
| 323.19 | 3.18 | 3.18 |
| 299.29 | 1.28 | 1.28 |
| 523.49 | 4.38 | 4.38 |
| 318.76 | 1.71 | 1.71 |
| 340.31 | 2.64 | 2.64 |
| 309.37 | 1.66 | 1.66 |
| 344.37 | 3.63 | 3.63 |
| 337.38 | 4.15 | 4.15 |
| 287.34 | 2.69 | 2.69 |
| 367.33 | 3.97 | 3.97 |
| 236.20 | 3.86 | 3.86 |
| 306.67 | 3.23 | 3.23 |
| 391.51 | 3.06 | 3.06 |
| 406.53 | 2.39 | 2.39 |
| 440.29 | 4.70 | 4.70 |
| 360.45 | 5.07 | 5.07 |
| 442.57 | 3.50 | 3.50 |
| 308.39 | 3.01 | 3.01 |
| 304.39 | 4.78 | 4.78 |
| 390.44 | 2.39 | 2.39 |
| 380.41 | 4.02 | 4.02 |
| 359.40 | 3.36 | 3.36 |
| 498.59 | 5.04 | 5.04 |
| 300.75 | 3.09 | 3.09 |
| 458.26 | 4.01 | 4.01 |
| 350.16 | 2.74 | 2.74 |
| 361.43 | 2.89 | 2.89 |
| 369.81 | 4.50 | 4.50 |
| 458.61 | 4.03 | 4.03 |
| 203.31 | 3.70 | 3.70 |
| 436.45 | 3.43 | 3.43 |
| 404.26 | 3.76 | 3.76 |
| 418.56 | 3.41 | 3.41 |
| 402.24 | 3.70 | 3.70 |
| 484.51 | 6.25 | 6.25 |
| 361.79 | 4.21 | 4.21 |
| 397.52 | 3.63 | 3.63 |
| 298.39 | 2.47 | 2.47 |
| 376.41 | 0.23 | 0.23 |
| 500.55 | 2.57 | 2.57 |
| 298.41 | 3.89 | 3.89 |
| 418.32 | 6.29 | 6.29 |
| 357.39 | 3.24 | 3.24 |
| 377.83 | 1.83 | 1.83 |
| 372.90 | 3.82 | 3.82 |
| 348.24 | 4.34 | 4.34 |
| 301.41 | 4.29 | 4.29 |
| 421.50 | 1.95 | 1.95 |
| 442.54 | 4.36 | 4.36 |
| 281.36 | 4.34 | 4.34 |
| 278.31 | 3.79 | 3.79 |
| 252.29 | 2.19 | 2.19 |
| 507.57 | 2.85 | 2.85 |
| 377.42 | 2.97 | 2.97 |
| 414.30 | 5.35 | 5.35 |
| 416.43 | 3.98 | 3.98 |
| 338.41 | 3.04 | 3.04 |
| 312.48 | 4.54 | 4.54 |
| 402.28 | 4.49 | 4.49 |
| 357.84 | 3.31 | 3.31 |
| 462.57 | 3.97 | 3.97 |
| 252.72 | 3.91 | 3.91 |
| 377.30 | 2.67 | 2.67 |
| 413.42 | 3.08 | 3.08 |
| 383.88 | 5.64 | 5.64 |
| 342.40 | 2.09 | 2.09 |
| 323.48 | 5.15 | 5.15 |
| 287.37 | 3.80 | 3.80 |
| 354.79 | 3.82 | 3.82 |
| 397.45 | 2.35 | 2.35 |
| 354.82 | 4.84 | 4.84 |
| 307.40 | 2.74 | 2.74 |
| 322.32 | 3.34 | 3.34 |
| 410.52 | 3.88 | 3.88 |
| 418.32 | 6.29 | 6.29 |
| 373.80 | 3.19 | 3.19 |
| 329.39 | 1.63 | 1.63 |
| 360.35 | 3.45 | 3.45 |
| 303.79 | 2.85 | 2.85 |
| 251.80 | 4.23 | 4.23 |
| 242.28 | 1.86 | 1.86 |
| 395.57 | 2.39 | 2.39 |
| 458.45 | 3.57 | 3.57 |
| 288.37 | 3.69 | 3.69 |
| 364.43 | 3.48 | 3.48 |
| 493.94 | 0.03 | 0.03 |
| 364.40 | 4.32 | 4.32 |
| 422.53 | 5.05 | 5.05 |
| 322.32 | 2.50 | 2.50 |
| 956.68 | 0.02 | 0.02 |
| 315.37 | 5.11 | 5.11 |
| 402.52 | 3.56 | 3.56 |
| 345.42 | 2.59 | 2.59 |
| 311.34 | 1.30 | 1.30 |
| 539.53 | 4.49 | 4.49 |
| 423.47 | 3.89 | 3.89 |
| 376.30 | 5.07 | 5.07 |
| 414.31 | 3.43 | 3.43 |
| 323.42 | 3.65 | 3.65 |
| 404.49 | 4.67 | 4.67 |
| 397.53 | 4.76 | 4.76 |
| 291.31 | 3.28 | 3.28 |
| 361.40 | 3.61 | 3.61 |
| 354.36 | 3.21 | 3.21 |
| 316.79 | 2.38 | 2.38 |
| 305.38 | 4.58 | 4.58 |
| 347.22 | 2.29 | 2.29 |
| 371.49 | 3.87 | 3.87 |
| 327.32 | 1.83 | 1.83 |
| 273.29 | 2.44 | 2.44 |
| 328.84 | 1.92 | 1.92 |
| 379.87 | 3.08 | 3.08 |
| 296.28 | 2.21 | 2.21 |
| 327.88 | 3.41 | 3.41 |
| 389.42 | 3.30 | 3.30 |
| 300.31 | 3.55 | 3.55 |
| 517.41 | -0.14 | -0.14 |
| 347.46 | 4.61 | 4.61 |
| 344.39 | 3.98 | 3.98 |
| 389.43 | 3.10 | 3.10 |
| 239.75 | 3.13 | 3.13 |
| 319.36 | 3.06 | 3.06 |
| 397.49 | 3.29 | 3.29 |
| 343.38 | 1.99 | 1.99 |
| 377.46 | 2.90 | 2.90 |
| 420.45 | 4.33 | 4.33 |
| 380.44 | 4.65 | 4.65 |
| 352.82 | 5.34 | 5.34 |
| 519.61 | 4.09 | 4.09 |
| 404.51 | 4.12 | 4.12 |
| 358.46 | 3.06 | 3.06 |
| 469.65 | 3.55 | 3.55 |
| 347.42 | 3.50 | 3.50 |
| 307.73 | 2.34 | 2.34 |
| 310.78 | 3.19 | 3.19 |
| 441.48 | 3.12 | 3.12 |
| 326.33 | 4.51 | 4.51 |
| 405.45 | 2.44 | 2.44 |
| 213.28 | 3.31 | 3.31 |
| 308.18 | 3.78 | 3.78 |
| 269.30 | 3.29 | 3.29 |
| 317.34 | 2.97 | 2.97 |
| 254.67 | 1.79 | 1.79 |
| 382.46 | 3.92 | 3.92 |
| 307.37 | 3.31 | 3.31 |
| 341.75 | 2.86 | 2.86 |
| 298.30 | 1.89 | 1.89 |
| 381.39 | 5.40 | 5.40 |
| 319.14 | 1.09 | 1.09 |
| 443.57 | 3.21 | 3.21 |
| 367.32 | 2.64 | 2.64 |
| 428.42 | 4.24 | 4.24 |
| 226.32 | 4.25 | 4.25 |
| 386.41 | 3.98 | 3.98 |
| 444.53 | 5.17 | 5.17 |
| 492.51 | 4.08 | 4.08 |
| 190.16 | 1.85 | 1.85 |
| 503.58 | 3.76 | 3.76 |
| 394.52 | 4.69 | 4.69 |
| 321.42 | 5.01 | 5.01 |
| 309.33 | 1.69 | 1.69 |
| 305.38 | 4.58 | 4.58 |
| 419.48 | 3.53 | 3.53 |
| 318.33 | 2.91 | 2.91 |
| 291.78 | 2.38 | 2.38 |
| 444.52 | 4.54 | 4.54 |
| 254.28 | 4.09 | 4.09 |
| 415.61 | 3.81 | 3.81 |
| 403.41 | 4.34 | 4.34 |
| 426.48 | 3.73 | 3.73 |
| 307.46 | 3.30 | 3.30 |
| 445.47 | 2.26 | 2.26 |
| 290.29 | 4.18 | 4.18 |
| 267.30 | 3.95 | 3.95 |
| 349.43 | 3.15 | 3.15 |
| 446.32 | 5.88 | 5.88 |
| 412.87 | 3.95 | 3.95 |
| 252.27 | 3.41 | 3.41 |
| 285.41 | 4.27 | 4.27 |
| 304.32 | 2.20 | 2.20 |
| 350.36 | 2.81 | 2.81 |
| 307.43 | 3.21 | 3.21 |
| 352.43 | 4.94 | 4.94 |
| 275.31 | 3.58 | 3.58 |
| 489.92 | 5.27 | 5.27 |
| 502.58 | 2.01 | 2.01 |
| 376.25 | 2.35 | 2.35 |
| 354.84 | 4.47 | 4.47 |
| 450.99 | 3.42 | 3.42 |
| 373.41 | 4.08 | 4.08 |
| 227.31 | 3.57 | 3.57 |
| 422.49 | 3.51 | 3.51 |
| 384.87 | 4.75 | 4.75 |
| 940.68 | 1.69 | 1.69 |
| 508.36 | 4.10 | 4.10 |
| 347.17 | 3.60 | 3.60 |
| 314.41 | 2.82 | 2.82 |
| 501.85 | 3.04 | 3.04 |
| 314.25 | 1.50 | 1.50 |
| 393.46 | 4.14 | 4.14 |
| 434.48 | 3.65 | 3.65 |
| 364.79 | 4.52 | 4.52 |
| 312.37 | 5.23 | 5.23 |
| 282.34 | 4.73 | 4.73 |
| 375.83 | 4.21 | 4.21 |
| 350.37 | 3.63 | 3.63 |
| 401.48 | 3.56 | 3.56 |
| 364.41 | 1.73 | 1.73 |
| 389.48 | 2.71 | 2.71 |
| 387.43 | 2.86 | 2.86 |
| 371.51 | 4.94 | 4.94 |
| 395.48 | 2.62 | 2.62 |
| 511.58 | 3.74 | 3.74 |
| 347.44 | 4.98 | 4.98 |
| 536.63 | 4.37 | 4.37 |
| 300.36 | 2.56 | 2.56 |
| 323.74 | 3.50 | 3.50 |
| 428.43 | 3.52 | 3.52 |
| 303.32 | 4.05 | 4.05 |
| 444.57 | 4.33 | 4.33 |
| 281.42 | 3.23 | 3.23 |
| 403.56 | 4.76 | 4.76 |
| 490.36 | 3.26 | 3.26 |
| 431.18 | 2.20 | 2.20 |
| 300.32 | 3.45 | 3.45 |
| 436.58 | 4.70 | 4.70 |
| 373.41 | 4.29 | 4.29 |
| 329.42 | 1.67 | 1.67 |
| 318.36 | 3.81 | 3.81 |
| 462.55 | 4.30 | 4.30 |
| 432.91 | 3.84 | 3.84 |
| 247.38 | 4.40 | 4.40 |
| 330.37 | 3.00 | 3.00 |
| 499.70 | 5.37 | 5.37 |
| 359.43 | 4.32 | 4.32 |
| 406.47 | 4.74 | 4.74 |
| 430.57 | 3.33 | 3.33 |
| 366.43 | 2.54 | 2.54 |
| 292.38 | 1.75 | 1.75 |
| 415.45 | 4.21 | 4.21 |
| 367.88 | 3.88 | 3.88 |
| 456.52 | 2.24 | 2.24 |
| 398.85 | 4.05 | 4.05 |
| 376.41 | 2.47 | 2.47 |
| 351.38 | 3.33 | 3.33 |
| 465.41 | 4.74 | 4.74 |
| 274.32 | 4.35 | 4.35 |
| 425.38 | 5.36 | 5.36 |
| 275.31 | 3.58 | 3.58 |
| 339.70 | 3.99 | 3.99 |
| 430.51 | 5.32 | 5.32 |
| 312.35 | 3.62 | 3.62 |
| 405.40 | 2.76 | 2.76 |
| 289.29 | 1.68 | 1.68 |
| 299.36 | 3.67 | 3.67 |
| 388.22 | 3.31 | 3.31 |
| 388.47 | 3.09 | 3.09 |
| 347.17 | 3.60 | 3.60 |
| 296.41 | 4.30 | 4.30 |
| 403.45 | 3.32 | 3.32 |
| 394.56 | 4.59 | 4.59 |
| 452.64 | 4.29 | 4.29 |
| 339.61 | 4.65 | 4.65 |
| 268.31 | 4.34 | 4.34 |
| 250.30 | 1.67 | 1.67 |
| 421.45 | 3.66 | 3.66 |
| 293.75 | 2.65 | 2.65 |
| 382.46 | 3.98 | 3.98 |
| 414.46 | 4.32 | 4.32 |
| 409.47 | 2.65 | 2.65 |
| 367.45 | 3.56 | 3.56 |
| 461.52 | 4.37 | 4.37 |
| 364.42 | 1.85 | 1.85 |
| 319.32 | 3.50 | 3.50 |
| 301.23 | 2.87 | 2.87 |
| 386.41 | 4.18 | 4.18 |
| 383.45 | 3.64 | 3.64 |
| 455.54 | 3.32 | 3.32 |
| 373.48 | 4.59 | 4.59 |
| 309.33 | 1.69 | 1.69 |
| 306.32 | 2.87 | 2.87 |
| 322.36 | 4.10 | 4.10 |
| 229.28 | 3.45 | 3.45 |
| 279.39 | 3.95 | 3.95 |
| 372.35 | 5.19 | 5.19 |
| 493.59 | 3.74 | 3.74 |
| 385.49 | 3.45 | 3.45 |
| 383.88 | 5.64 | 5.64 |
| 243.69 | 3.23 | 3.23 |
| 296.39 | 2.92 | 2.92 |
| 307.34 | 3.69 | 3.69 |
| 446.89 | 2.72 | 2.72 |
| 380.49 | 4.64 | 4.64 |
| 432.38 | 0.09 | 0.09 |
| 395.44 | 4.34 | 4.34 |
| 277.28 | 3.26 | 3.26 |
| 392.44 | 1.83 | 1.83 |
| 317.43 | 3.21 | 3.21 |
| 323.37 | 4.72 | 4.72 |
| 333.34 | 1.70 | 1.70 |
| 264.33 | 3.41 | 3.41 |
| 374.48 | 3.16 | 3.16 |
| 250.21 | -0.24 | -0.24 |
| 284.70 | 3.60 | 3.60 |
| 924.09 | 0.71 | 0.71 |
| 465.55 | 4.79 | 4.79 |
| 218.21 | 0.59 | 0.59 |
| 418.45 | 5.87 | 5.87 |
| 277.71 | 2.43 | 2.43 |
| 390.34 | 2.45 | 2.45 |
| 389.24 | 0.54 | 0.54 |
| 446.40 | 2.39 | 2.39 |
| 456.56 | 2.85 | 2.85 |
| 385.42 | 2.57 | 2.57 |
| 301.44 | 3.61 | 3.61 |
| 465.50 | 2.84 | 2.84 |
| 237.26 | 2.57 | 2.57 |
| 303.41 | 3.18 | 3.18 |
| 450.62 | 6.70 | 6.70 |
| 319.39 | 2.11 | 2.11 |
| 448.52 | 1.59 | 1.59 |
| 404.46 | 5.06 | 5.06 |
| 340.39 | 2.71 | 2.71 |
| 427.57 | 2.52 | 2.52 |
| 277.28 | 2.38 | 2.38 |
| 240.78 | 2.92 | 2.92 |
| 430.35 | 2.95 | 2.95 |
| 300.31 | 3.74 | 3.74 |
| 714.68 | 2.70 | 2.70 |
| 630.79 | 5.99 | 5.99 |
| 534.41 | 5.39 | 5.39 |
| 304.40 | 4.15 | 4.15 |
| 229.24 | 2.37 | 2.37 |
| 557.59 | 4.21 | 4.21 |
| 255.23 | 1.12 | 1.12 |
| 326.37 | 3.47 | 3.47 |
| 299.37 | 4.29 | 4.29 |
| 365.38 | 4.03 | 4.03 |
| 416.48 | 4.53 | 4.53 |
| 294.38 | 4.27 | 4.27 |
| 462.64 | 2.59 | 2.59 |
| 373.41 | 4.07 | 4.07 |
| 593.22 | 7.93 | 7.93 |
| 546.16 | 7.01 | 7.01 |
| 305.76 | 2.63 | 2.63 |
| 447.56 | 4.81 | 4.81 |
| 264.24 | 1.36 | 1.36 |
| 482.65 | 5.95 | 5.95 |
| 379.29 | 3.44 | 3.44 |
| 291.35 | 1.09 | 1.09 |
| 713.80 | 7.31 | 7.31 |
| 306.82 | 3.16 | 3.16 |
| 313.35 | 2.60 | 2.60 |
| 724.84 | 6.04 | 6.04 |
| 297.35 | 3.83 | 3.83 |
| 285.14 | 2.60 | 2.60 |
| 522.65 | 7.46 | 7.46 |
| 244.21 | 2.75 | 2.75 |
| 416.50 | 4.91 | 4.91 |
| 199.21 | 1.11 | 1.11 |
| 329.38 | 2.53 | 2.53 |
| 231.90 | 2.69 | 2.69 |
| 367.49 | 3.67 | 3.67 |
| 366.51 | 3.28 | 3.28 |
| 206.15 | 0.34 | 0.34 |
| 410.44 | 3.53 | 3.53 |
| 282.34 | 3.17 | 3.17 |
| 482.00 | 5.84 | 5.84 |
| 357.39 | 2.90 | 2.90 |
| 272.26 | 1.96 | 1.96 |
| 432.82 | 6.17 | 6.17 |
| 406.24 | 3.65 | 3.65 |
| 339.48 | 4.84 | 4.84 |
| 279.43 | 2.73 | 2.73 |
| 391.47 | 2.82 | 2.82 |
| 403.41 | 4.00 | 4.00 |
| 318.38 | 4.06 | 4.06 |
| 321.77 | 5.00 | 5.00 |
| 244.32 | 2.91 | 2.91 |
| 360.37 | 3.51 | 3.51 |
| 303.36 | 4.72 | 4.72 |
| 387.03 | 3.27 | 3.27 |
| 286.36 | 3.55 | 3.55 |
| 315.35 | 2.63 | 2.63 |
| 385.22 | 3.82 | 3.82 |
| 396.54 | 3.92 | 3.92 |
| 376.43 | 3.13 | 3.13 |
| 320.39 | 2.90 | 2.90 |
| 360.46 | 2.40 | 2.40 |
| 272.26 | 0.95 | 0.95 |
| 347.37 | 4.36 | 4.36 |
| 425.30 | 3.43 | 3.43 |
| 307.35 | 2.64 | 2.64 |
| 332.34 | 2.33 | 2.33 |
| 325.39 | 3.18 | 3.18 |
| 268.32 | 3.87 | 3.87 |
| 424.48 | 2.40 | 2.40 |
| 289.36 | 2.24 | 2.24 |
| 407.45 | 1.60 | 1.60 |
| 437.36 | 3.46 | 3.46 |
| 431.48 | 3.78 | 3.78 |
| 324.41 | 0.23 | 0.23 |
| 372.39 | 2.02 | 2.02 |
| 360.85 | 5.28 | 5.28 |
| 293.35 | 1.78 | 1.78 |
| 297.41 | 2.83 | 2.83 |
| 299.37 | 3.26 | 3.26 |
| 319.45 | 4.77 | 4.77 |
| 513.94 | 3.11 | 3.11 |
| 347.42 | 2.81 | 2.81 |
| 349.84 | 3.09 | 3.09 |
| 426.43 | 6.13 | 6.13 |
| 552.67 | 3.12 | 3.12 |
| 417.45 | 3.47 | 3.47 |
| 328.33 | 2.30 | 2.30 |
| 307.35 | 2.59 | 2.59 |
| 332.79 | 2.53 | 2.53 |
| 339.42 | 3.74 | 3.74 |