ID: ALA3562060
Type: Functional
Description: PubChem BioAssay. Dose response counterscreen for inhibitors of viability of late stage Plasmodium falciparum gametocytes: Luminescence-based cell-based high throughput dose response assay to identify compounds that are cytotoxic to Jurkat human T lymphocyte cells.. (Class of assay: confirmatory)
Cell type: Jurkat
Bioactivity
Activity Types for Assay ALA3562060
IC50
Parent Molecular Weight | ALogP | Polar Surface Area |
---|---|---|
285.28 | 0.37 | 0.37 |
144.22 | -0.33 | -0.33 |
317.41 | 2.29 | 2.29 |
444.27 | 6.03 | 6.03 |
422.51 | 4.11 | 4.11 |
271.32 | 4.09 | 4.09 |
344.44 | 2.14 | 2.14 |
440.59 | 3.01 | 3.01 |
485.59 | 4.53 | 4.53 |
379.46 | 3.02 | 3.02 |
172.27 | 0.04 | 0.04 |
445.50 | 4.49 | 4.49 |
355.23 | 2.84 | 2.84 |
274.32 | 2.00 | 2.00 |
305.36 | 2.93 | 2.93 |
387.46 | 3.94 | 3.94 |
324.43 | 3.26 | 3.26 |
249.70 | 3.33 | 3.33 |
262.32 | 2.98 | 2.98 |
259.31 | 3.50 | 3.50 |
461.59 | 3.67 | 3.67 |
311.41 | 3.48 | 3.48 |
294.31 | 2.22 | 2.22 |
513.69 | 3.64 | 3.64 |
295.30 | 3.11 | 3.11 |
227.22 | 1.27 | 1.27 |
457.37 | 3.68 | 3.68 |
345.44 | 3.63 | 3.63 |
338.41 | 3.24 | 3.24 |
429.31 | 1.88 | 1.88 |
247.30 | 2.83 | 2.83 |
378.40 | 4.45 | 4.45 |
328.28 | 1.60 | 1.60 |
344.42 | 1.24 | 1.24 |
299.37 | 4.49 | 4.49 |
316.51 | 5.08 | 5.08 |
331.33 | 2.13 | 2.13 |
298.90 | 2.89 | 2.89 |
265.34 | 1.16 | 1.16 |
369.45 | 2.29 | 2.29 |
287.17 | 4.40 | 4.40 |
245.30 | 2.40 | 2.40 |
325.52 | 2.79 | 2.79 |
264.33 | 2.87 | 2.87 |
407.54 | 5.32 | 5.32 |
354.19 | 4.34 | 4.34 |
388.42 | 3.50 | 3.50 |
269.30 | 3.09 | 3.09 |
322.79 | 3.82 | 3.82 |
509.58 | 4.59 | 4.59 |
331.46 | 2.34 | 2.34 |
379.44 | 3.97 | 3.97 |
335.40 | 3.42 | 3.42 |
377.49 | 5.80 | 5.80 |
491.65 | 3.40 | 3.40 |
486.62 | 2.91 | 2.91 |
418.52 | 3.09 | 3.09 |
291.28 | 1.82 | 1.82 |
275.26 | 1.41 | 1.41 |
135.17 | 1.20 | 1.20 |
438.44 | 0.99 | 0.99 |
489.92 | 5.70 | 5.70 |
350.77 | 4.23 | 4.23 |
326.44 | 3.02 | 3.02 |
418.52 | 2.06 | 2.06 |
548.75 | 2.24 | 2.24 |
307.42 | 2.70 | 2.70 |
310.42 | 3.29 | 3.29 |
413.50 | 2.46 | 2.46 |
301.31 | 2.73 | 2.73 |
417.52 | 3.34 | 3.34 |
288.37 | 2.59 | 2.59 |
379.53 | 2.05 | 2.05 |
450.49 | 3.10 | 3.10 |
305.36 | 2.11 | 2.11 |
386.52 | 2.95 | 2.95 |
279.30 | 2.64 | 2.64 |
257.32 | 2.81 | 2.81 |
241.29 | 3.32 | 3.32 |
427.91 | 2.50 | 2.50 |
296.37 | 5.27 | 5.27 |
281.31 | 2.67 | 2.67 |
297.42 | 2.92 | 2.92 |
287.34 | 2.56 | 2.56 |
344.50 | 3.09 | 3.09 |
366.87 | 3.82 | 3.82 |
202.26 | 2.13 | 2.13 |
324.34 | 2.61 | 2.61 |
393.75 | 5.05 | 5.05 |
331.76 | 3.25 | 3.25 |
221.69 | 2.60 | 2.60 |
215.21 | 2.15 | 2.15 |
468.46 | 2.50 | 2.50 |
267.28 | 1.00 | 1.00 |
387.44 | 2.46 | 2.46 |
228.29 | 2.74 | 2.74 |
255.31 | -0.21 | -0.21 |
281.32 | 3.33 | 3.33 |
394.88 | 5.62 | 5.62 |
233.27 | 1.74 | 1.74 |
371.39 | 3.00 | 3.00 |
474.59 | 3.25 | 3.25 |
255.12 | 2.75 | 2.75 |
217.23 | 1.31 | 1.31 |
317.39 | 5.22 | 5.22 |
430.53 | 3.27 | 3.27 |
363.46 | 4.05 | 4.05 |
298.36 | 0.38 | 0.38 |
379.49 | 3.67 | 3.67 |
390.44 | 1.29 | 1.29 |
397.39 | 1.06 | 1.06 |
328.38 | 3.80 | 3.80 |
334.51 | 4.07 | 4.07 |
413.45 | 3.68 | 3.68 |
392.89 | 1.73 | 1.73 |
372.92 | 2.72 | 2.72 |
350.40 | 2.46 | 2.46 |
289.38 | 0.49 | 0.49 |
487.58 | 2.14 | 2.14 |
270.40 | 4.15 | 4.15 |
228.25 | 2.34 | 2.34 |
364.43 | 3.21 | 3.21 |
448.55 | 3.75 | 3.75 |
415.52 | 3.25 | 3.25 |
276.30 | 2.57 | 2.57 |
327.38 | 3.58 | 3.58 |
287.36 | 0.77 | 0.77 |
283.33 | 3.07 | 3.07 |
459.57 | 4.40 | 4.40 |
403.44 | 3.30 | 3.30 |
435.52 | 3.08 | 3.08 |
178.19 | 1.09 | 1.09 |
398.44 | 2.38 | 2.38 |
266.30 | 1.93 | 1.93 |
409.46 | 3.52 | 3.52 |
302.31 | 3.87 | 3.87 |
363.46 | 4.52 | 4.52 |
375.50 | 5.00 | 5.00 |
373.25 | 4.02 | 4.02 |
258.37 | 3.96 | 3.96 |
407.94 | 4.61 | 4.61 |
362.41 | 4.26 | 4.26 |
333.41 | 4.04 | 4.04 |
398.42 | 4.15 | 4.15 |
289.27 | 3.05 | 3.05 |
296.33 | 3.69 | 3.69 |
315.71 | 3.03 | 3.03 |
266.32 | 1.40 | 1.40 |
387.42 | 1.66 | 1.66 |
393.19 | 5.08 | 5.08 |
347.40 | 3.64 | 3.64 |
268.27 | 2.61 | 2.61 |
234.28 | 1.88 | 1.88 |
169.18 | 1.73 | 1.73 |
287.34 | 3.22 | 3.22 |
486.57 | 3.58 | 3.58 |
366.44 | 2.92 | 2.92 |
285.30 | 2.90 | 2.90 |
277.20 | 4.23 | 4.23 |
326.19 | 1.25 | 1.25 |
325.80 | 2.94 | 2.94 |
411.48 | 2.50 | 2.50 |
391.41 | 3.33 | 3.33 |
172.28 | -1.48 | -1.48 |
302.44 | 4.34 | 4.34 |
333.41 | 1.94 | 1.94 |
478.59 | 2.56 | 2.56 |
315.42 | 2.43 | 2.43 |
353.37 | 3.22 | 3.22 |
349.82 | 2.37 | 2.37 |
264.24 | 1.24 | 1.24 |
374.31 | 4.39 | 4.39 |
220.26 | 1.49 | 1.49 |
324.38 | 2.01 | 2.01 |
342.38 | 3.75 | 3.75 |
286.28 | 2.63 | 2.63 |
279.38 | 3.95 | 3.95 |
570.04 | 7.53 | 7.53 |
357.41 | 5.68 | 5.68 |
407.47 | 3.92 | 3.92 |
300.32 | 1.65 | 1.65 |
473.57 | 4.82 | 4.82 |
282.41 | 2.04 | 2.04 |
219.33 | 2.78 | 2.78 |
348.42 | 1.81 | 1.81 |
284.32 | 1.98 | 1.98 |
410.54 | 4.13 | 4.13 |
508.64 | 3.84 | 3.84 |
343.43 | 3.01 | 3.01 |
279.30 | 2.10 | 2.10 |
379.47 | 1.79 | 1.79 |
411.49 | 3.18 | 3.18 |
428.47 | 1.06 | 1.06 |
263.29 | 1.97 | 1.97 |
366.43 | 2.97 | 2.97 |
303.38 | 2.90 | 2.90 |
465.60 | 1.61 | 1.61 |
297.31 | 1.77 | 1.77 |
302.23 | 4.36 | 4.36 |
286.36 | 1.67 | 1.67 |
359.50 | 3.56 | 3.56 |
284.35 | 2.53 | 2.53 |
382.42 | 2.76 | 2.76 |
381.48 | 3.22 | 3.22 |
471.33 | 2.26 | 2.26 |
234.30 | 2.60 | 2.60 |
412.29 | 2.35 | 2.35 |
276.25 | 1.48 | 1.48 |
365.82 | 5.05 | 5.05 |
483.46 | 5.13 | 5.13 |
421.52 | 1.00 | 1.00 |
262.27 | 2.26 | 2.26 |
291.33 | 0.44 | 0.44 |
467.59 | 0.10 | 0.10 |
274.25 | 2.02 | 2.02 |
340.42 | 3.36 | 3.36 |
235.33 | 2.54 | 2.54 |
390.53 | 3.25 | 3.25 |
357.39 | 3.12 | 3.12 |
572.68 | 4.76 | 4.76 |
342.44 | 3.19 | 3.19 |
416.32 | 3.45 | 3.45 |
341.80 | 0.57 | 0.57 |
330.38 | 2.46 | 2.46 |
298.38 | 3.97 | 3.97 |
475.34 | 3.24 | 3.24 |
324.41 | 2.47 | 2.47 |
310.35 | 2.41 | 2.41 |
544.55 | 4.88 | 4.88 |
255.34 | 1.87 | 1.87 |
192.29 | 1.88 | 1.88 |
437.31 | 3.40 | 3.40 |
254.33 | 2.89 | 2.89 |
363.30 | 3.39 | 3.39 |
299.44 | 2.00 | 2.00 |
258.11 | 2.34 | 2.34 |
461.56 | 2.11 | 2.11 |
311.39 | 2.64 | 2.64 |
345.47 | 0.30 | 0.30 |
306.41 | 1.13 | 1.13 |
399.49 | 3.17 | 3.17 |
277.30 | 2.46 | 2.46 |
518.57 | 3.04 | 3.04 |
321.40 | 3.12 | 3.12 |