Basic Information
ID: ALA3562122
Type: Functional
Description: PubChem BioAssay. Fluorescence-based biochemical high throughput dose response assay to identify inhibitors of Trypanosoma brucei RNA editing ligase 1 (TbREL1).. (Class of assay: confirmatory)
Activity Charts
Bioactivity
Activity Types for Assay ALA3562122
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 223.62 | 1.64 | 1.64 |
| 167.12 | 0.48 | 0.48 |
| 316.26 | 2.29 | 2.29 |
| 210.19 | 1.52 | 1.52 |
| 464.38 | 0.19 | 0.19 |
| 207.19 | -1.32 | -1.32 |
| 458.74 | 4.97 | 4.97 |
| 306.27 | 2.00 | 2.00 |
| 367.45 | 2.87 | 2.87 |
| 315.51 | 5.16 | 5.16 |
| 419.57 | 5.80 | 5.80 |
| 494.59 | 4.84 | 4.84 |
| 235.25 | -0.67 | -0.67 |
| 461.48 | 4.30 | 4.30 |
| 316.24 | 1.54 | 1.54 |
| 364.41 | 2.49 | 2.49 |
| 379.46 | 3.02 | 3.02 |
| 402.28 | 5.66 | 5.66 |
| 346.35 | 5.18 | 5.18 |
| 396.41 | -1.07 | -1.07 |
| 502.70 | 4.68 | 4.68 |
| 412.42 | 3.16 | 3.16 |
| 480.94 | 7.28 | 7.28 |
| 455.55 | 5.00 | 5.00 |
| 409.87 | 4.52 | 4.52 |
| 234.69 | 1.78 | 1.78 |
| 363.37 | 3.26 | 3.26 |
| 318.76 | 2.64 | 2.64 |
| 355.44 | 2.73 | 2.73 |
| 569.58 | 5.73 | 5.73 |
| 411.45 | 3.93 | 3.93 |
| 283.36 | 2.32 | 2.32 |
| 245.27 | 1.15 | 1.15 |
| 535.71 | 5.13 | 5.13 |
| 415.02 | 6.09 | 6.09 |
| 438.32 | 4.62 | 4.62 |
| 406.44 | 4.41 | 4.41 |
| 234.19 | 0.13 | 0.13 |
| 341.89 | 5.23 | 5.23 |
| 316.31 | 3.87 | 3.87 |
| 545.49 | 5.00 | 5.00 |
| 493.59 | 3.25 | 3.25 |
| 439.57 | 3.66 | 3.66 |
| 224.27 | 2.39 | 2.39 |
| 344.93 | 4.80 | 4.80 |
| 443.52 | 4.98 | 4.98 |
| 364.43 | 2.77 | 2.77 |
| 363.40 | 4.37 | 4.37 |
| 573.18 | 5.42 | 5.42 |
| 371.37 | 3.29 | 3.29 |
| 281.27 | 1.18 | 1.18 |
| 355.44 | 2.73 | 2.73 |
| 502.70 | 4.68 | 4.68 |
| 527.51 | 4.51 | 4.51 |
| 475.51 | 1.17 | 1.17 |
| 400.99 | 5.70 | 5.70 |
| 387.48 | 4.33 | 4.33 |
| 405.82 | 3.94 | 3.94 |
| 365.30 | 3.59 | 3.59 |
| 396.61 | 3.99 | 3.99 |
| 401.89 | 3.81 | 3.81 |
| 357.81 | 5.13 | 5.13 |
| 395.93 | 3.90 | 3.90 |
| 421.43 | 2.39 | 2.39 |
| 234.28 | 2.07 | 2.07 |
| 390.51 | 2.37 | 2.37 |
| 564.65 | 5.01 | 5.01 |
| 312.24 | 0.24 | 0.24 |
| 437.55 | 5.30 | 5.30 |
| 376.49 | 4.92 | 4.92 |
| 438.98 | 6.32 | 6.32 |
| 477.56 | 5.42 | 5.42 |
| 410.81 | 3.73 | 3.73 |
| 333.26 | 0.78 | 0.78 |
| 541.55 | 6.00 | 6.00 |
| 279.32 | 1.39 | 1.39 |
| 293.35 | 1.78 | 1.78 |
| 352.44 | 2.83 | 2.83 |
| 378.41 | 0.79 | 0.79 |
| 499.46 | 5.69 | 5.69 |
| 523.56 | 5.86 | 5.86 |
| 629.52 | 7.89 | 7.89 |
| 475.49 | 5.20 | 5.20 |
| 579.52 | 7.01 | 7.01 |
| 435.42 | 4.42 | 4.42 |
| 595.97 | 7.53 | 7.53 |
| 1059.77 | ||
| 558.00 | 6.52 | 6.52 |
| 595.97 | 7.53 | 7.53 |
| 461.46 | 4.98 | 4.98 |
| 629.52 | 7.89 | 7.89 |
| 591.55 | 6.88 | 6.88 |
| 558.00 | 6.52 | 6.52 |
| 511.47 | 5.86 | 5.86 |
| 595.97 | 7.53 | 7.53 |
| 571.98 | 6.24 | 6.24 |
| 629.52 | 7.89 | 7.89 |
| 1001.73 | 1.28 | 1.28 |
| 579.52 | 7.01 | 7.01 |
| 611.66 | 6.14 | 6.14 |
| 629.52 | 7.89 | 7.89 |
| 381.45 | 1.44 | 1.44 |
| 605.54 | 6.60 | 6.60 |
| 527.97 | 6.51 | 6.51 |
| 430.42 | -1.01 | -1.01 |
| 591.55 | 6.88 | 6.88 |
| 561.53 | 6.87 | 6.87 |
| 579.52 | 7.01 | 7.01 |
| 605.54 | 6.60 | 6.60 |
| 541.55 | 6.00 | 6.00 |
| 561.53 | 6.87 | 6.87 |
| 629.52 | 7.89 | 7.89 |
| 525.49 | 6.08 | 6.08 |
| 397.45 | 0.67 | 0.67 |
| 629.52 | 7.89 | 7.89 |
| 651.60 | 6.90 | 6.90 |
| 511.52 | 5.99 | 5.99 |
| 605.54 | 6.60 | 6.60 |
| 525.49 | 6.08 | 6.08 |
| 511.47 | 5.86 | 5.86 |
| 532.77 | 4.85 | 4.85 |
| 555.53 | 5.72 | 5.72 |
| 629.52 | 7.89 | 7.89 |
| 561.53 | 6.87 | 6.87 |
| 537.54 | 5.58 | 5.58 |
| 461.46 | 4.98 | 4.98 |
| 521.58 | 6.12 | 6.12 |
| 566.79 | 5.05 | 5.05 |
| 629.52 | 7.89 | 7.89 |
| 542.50 | 2.01 | 2.01 |