Basic Information
ID: ALA3578337
Type: Binding
Description: Inhibition of wild type CRAF (unknown origin) assessed as ADP formation measured for 5 hrs by pyruvate kinase/lactate dehydrogenase coupled assay in presence of ATP, MEK1, PEP, NADH
Format: BAO_0000357
Organism: Homo sapiens
Target: Serine/threonine-protein kinase RAF(ALA1906)
Document: ALA3576847
Inhibition of wild type CRAF (unknown origin) assessed as ADP formation measured for 5 hrs by pyruvate kinase/lactate dehydrogenase coupled assay in presence of ATP, MEK1, PEP, NADH: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3578337
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 489.93 | 5.54 | 5.54 |
| 520.57 | 5.14 | 5.14 |
| 478.53 | 5.19 | 5.19 |
| 453.56 | 5.13 | 5.13 |
| 439.54 | 4.62 | 4.62 |
| 405.55 | 5.51 | 5.51 |
| 410.50 | 4.74 | 4.74 |
| 409.51 | 5.34 | 5.34 |
| 423.54 | 5.65 | 5.65 |
| 410.50 | 4.74 | 4.74 |
| 424.52 | 5.05 | 5.05 |