Basic Information
ID: ALA3578971
Type: Functional
Description: Inhibition of RANKL-induced fusion of preosteoclast derived from ICR mouse bone marrow-derived macrophages assessed as formation of tartrate-resistant acid phosphatase-positive multinucleated osteoclast preincubated for 30 mins with M-CSF followed by RANKL induction measured after 1 day by TRAP staining
Format: BAO_0000219
Organism: Mus musculus
Strain: ICR
Cell type: Osteoclast
Target: Tumor necrosis factor ligand superfamily member 11(ALA3596084)
Document: ALA3576801
Inhibition of RANKL-induced fusion of preosteoclast derived from ICR mouse bone marrow-derived macrophages assessed as formation of tartrate-resistant acid phosphatase-positive multinucleated osteoclast preincubated for 30 mins with M-CSF followed by RANKL induction measured after 1 day by TRAP staining: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3578971
Inhibition
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 386.40 | 3.45 | 3.45 |