Basic Information
ID: ALA3578998
Type: Binding
Description: Antagonist activity at human mineralocorticoid receptor overexpressed in CHOK1 cells assessed as inhibition of aldosterone-induced protein interaction with coactivator peptide after 6 hrs by luminescence assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: CHO-K1
Target: Mineralocorticoid receptor(ALA1994)
Document: ALA3576820
Antagonist activity at human mineralocorticoid receptor overexpressed in CHOK1 cells assessed as inhibition of aldosterone-induced protein interaction with coactivator peptide after 6 hrs by luminescence assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3578998
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 463.90 | 5.53 | 5.53 |
| 429.45 | 4.88 | 4.88 |
| 447.44 | 5.02 | 5.02 |
| 497.45 | 5.90 | 5.90 |
| 513.45 | 5.78 | 5.78 |
| 522.56 | 4.25 | 4.25 |
| 486.50 | 4.84 | 4.84 |
| 486.50 | 4.24 | 4.24 |
| 454.46 | 4.75 | 4.75 |
| 497.49 | 3.86 | 3.86 |
| 495.51 | 5.27 | 5.27 |
| 509.54 | 5.28 | 5.28 |
| 495.51 | 5.27 | 5.27 |
| 496.50 | 5.54 | 5.54 |
| 510.53 | 5.84 | 5.84 |
| 514.56 | 4.72 | 4.72 |
| 506.54 | 5.94 | 5.94 |
| 506.54 | 5.94 | 5.94 |
| 506.54 | 5.94 | 5.94 |
| 540.98 | 6.60 | 6.60 |
| 507.53 | 5.34 | 5.34 |
| 447.44 | 5.02 | 5.02 |
| 463.90 | 5.53 | 5.53 |
| 497.45 | 5.90 | 5.90 |
| 486.50 | 4.84 | 4.84 |
| 522.56 | 4.25 | 4.25 |
| 496.50 | 5.54 | 5.54 |
| 495.51 | 5.27 | 5.27 |
| 509.54 | 5.28 | 5.28 |
| 506.54 | 5.94 | 5.94 |
| 506.54 | 5.94 | 5.94 |
| 507.53 | 5.34 | 5.34 |