Basic Information
ID: ALA3579066
Type: Binding
Description: Inhibition of JNK in human SH-SY5Y cells assessed as inhibition of 6-OHDA-induced c-Jun phosphorylation preincubated for 1 hr followed by 6-OHDA-induction measured after 4 to 5 hrs by Western blot analysis
Format: BAO_0000219
Organism: Homo sapiens
Cell type: SH-SY5Y
Target: c-Jun N-terminal kinase, JNK(ALA2096667)
Document: ALA3576797
Inhibition of JNK in human SH-SY5Y cells assessed as inhibition of 6-OHDA-induced c-Jun phosphorylation preincubated for 1 hr followed by 6-OHDA-induction measured after 4 to 5 hrs by Western blot analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3579066
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 371.49 | 2.87 | 2.87 |
| 372.47 | 2.41 | 2.41 |
| 386.50 | 2.80 | 2.80 |
| 372.47 | 2.41 | 2.41 |
| 358.45 | 1.98 | 1.98 |
| 412.54 | 3.34 | 3.34 |