Basic Information
ID: ALA3579067
Type: Binding
Description: Inhibition of JNK in human SH-SY5Y cells assessed as inhibition of 6-OHDA-induced mitochondrial membrane depolarization preincubated for 30 mins followed by 6-OHDA-induction measured after 4 to 5 hrs by mitoTracker orange CMTRos dye-based fluorescence assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: SH-SY5Y
Target: c-Jun N-terminal kinase, JNK(ALA2096667)
Document: ALA3576797
Inhibition of JNK in human SH-SY5Y cells assessed as inhibition of 6-OHDA-induced mitochondrial membrane depolarization preincubated for 30 mins followed by 6-OHDA-induction measured after 4 to 5 hrs by mitoTracker orange CMTRos dye-based fluorescence assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3579067
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 371.49 | 2.87 | 2.87 |
| 386.50 | 2.80 | 2.80 |