Orthosteric non-competitive inhibition of human ASIC1a endogenously expressed in HEK293 cells clamped at -100 mV gated ionic current assessed as EC50 ...

ID: ALA3579920

Type: Binding

Description: Orthosteric non-competitive inhibition of human ASIC1a endogenously expressed in HEK293 cells clamped at -100 mV gated ionic current assessed as EC50 for steady state activation at 10 nM by standard whole cell patch clamp assay (Rvb = 6.57 +/- 0.01 pH)

Format: BAO_0000219

Organism: Homo sapiens

Cell type: HEK293

Target:  Amiloride-sensitive cation channel 2, neuronal(ALA1628477)

Document:  ALA3576804

Orthosteric non-competitive inhibition of human ASIC1a endogenously expressed in HEK293 cells clamped at -100 mV gated ionic current assessed as EC50 for steady state activation at 10 nM by standard whole cell patch clamp assay (Rvb = 6.57 +/- 0.01 pH): 1