Basic Information
ID: ALA3579920
Type: Binding
Description: Orthosteric non-competitive inhibition of human ASIC1a endogenously expressed in HEK293 cells clamped at -100 mV gated ionic current assessed as EC50 for steady state activation at 10 nM by standard whole cell patch clamp assay (Rvb = 6.57 +/- 0.01 pH)
Organism: Homo sapiens
Cell type: HEK293
Activity Charts
Bioactivity
Activity Types for Assay ALA3579920
EC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 426.95 | 4.08 | 4.08 |