Basic Information
ID: ALA3579923
Type: Binding
Description: Orthosteric non-competitive inhibition of human ASIC1a endogenously expressed in HEK293 cells clamped at -100 mV gated ionic current assessed as maximal evoked response for steady-state activation at 10 nM by standard whole cell patch clamp assay relative to untreated control
Format: BAO_0000219
Organism: Homo sapiens
Cell type: HEK293
Target: Amiloride-sensitive cation channel 2, neuronal(ALA1628477)
Document: ALA3576804
Orthosteric non-competitive inhibition of human ASIC1a endogenously expressed in HEK293 cells clamped at -100 mV gated ionic current assessed as maximal evoked response for steady-state activation at 10 nM by standard whole cell patch clamp assay relative to untreated control: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3579923
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 426.95 | 4.08 | 4.08 |