Basic Information
ID: ALA3580054
Type: Binding
Description: Activity of TOP2 in human K562 cells assessed as poisoning activity by measuring phosphorylation of gamma-H2AX at Ser139 at 100 uM after 1 hr by DAPI staining-based epifluorescence microscopic analysis
Format: BAO_0000219
Organism: Homo sapiens
Cell type: K562
Target: Unchecked(ALA612545)
Document: ALA3576785
Activity of TOP2 in human K562 cells assessed as poisoning activity by measuring phosphorylation of gamma-H2AX at Ser139 at 100 uM after 1 hr by DAPI staining-based epifluorescence microscopic analysis: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3580054
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 588.56 | 1.34 | 1.34 |
| 508.53 | 2.32 | 2.32 |
| 566.61 | 2.87 | 2.87 |
| 573.56 | 3.62 | 3.62 |
| 609.63 | 3.66 | 3.66 |
| 629.62 | 3.97 | 3.97 |