Modulation of MRP1 (unknown origin) transfected in human 2008/MRP1 cells assessed as potentiation of doxorubicin-induced cytotoxicity measured as doxo...

Basic Information

ID: ALA3584584

Type: Binding

Description: Modulation of MRP1 (unknown origin) transfected in human 2008/MRP1 cells assessed as potentiation of doxorubicin-induced cytotoxicity measured as doxorubicin IC50 at 1 uM after 5 days by MTS assay relative to doxorubicin alone treated cell

Format: BAO_0000219

Organism: Homo sapiens

Cell type: 2008/MRP1

Target:  Multidrug resistance-associated protein 1(ALA3004)

Document:  ALA3580553

Modulation of MRP1 (unknown origin) transfected in human 2008/MRP1 cells assessed as potentiation of doxorubicin-induced cytotoxicity measured as doxorubicin IC50 at 1 uM after 5 days by MTS assay relative to doxorubicin alone treated cell: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
469.583.643.64
596.635.065.06
677.686.046.04
707.706.056.05
677.686.046.04
707.706.056.05