Basic Information
ID: ALA3585162
Type: Binding
Description: Inhibition of recombinant topoisomerase 1 (unknown origin) assessed as DNA cleavage using 3'-[32P]-labeled 117-bp DNA oligonucleotide at 1 uM by PAGE assay
Organism: Homo sapiens
Activity Charts
Bioactivity
Activity Types for Assay ALA3585162
Activity
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 348.36 | 2.08 | 2.08 |
| 421.45 | 1.85 | 1.85 |
| 400.39 | 3.41 | 3.41 |
| 419.44 | 2.84 | 2.84 |
| 366.33 | 1.47 | 1.47 |
| 380.41 | 3.37 | 3.37 |
| 399.45 | 2.81 | 2.81 |
| 434.29 | 4.26 | 4.26 |
| 453.34 | 3.70 | 3.70 |
| 413.43 | 3.29 | 3.29 |
| 432.48 | 2.72 | 2.72 |
| 339.32 | 1.71 | 1.71 |
| 373.39 | 3.64 | 3.64 |
| 392.43 | 3.07 | 3.07 |
| 355.78 | 2.22 | 2.22 |
| 389.84 | 4.15 | 4.15 |
| 408.89 | 3.59 | 3.59 |
| 400.23 | 2.33 | 2.33 |
| 447.23 | 2.17 | 2.17 |
| 481.29 | 4.10 | 4.10 |
| 500.34 | 3.54 | 3.54 |
| 346.34 | 1.44 | 1.44 |
| 389.33 | 2.58 | 2.58 |
| 423.39 | 4.52 | 4.52 |
| 389.33 | 2.58 | 2.58 |
| 423.39 | 4.52 | 4.52 |
| 367.43 | 2.29 | 2.29 |
| 401.49 | 4.22 | 4.22 |
| 399.42 | 0.97 | 0.97 |
| 433.49 | 2.90 | 2.90 |
| 379.37 | 1.35 | 1.35 |
| 375.43 | 2.33 | 2.33 |
| 333.39 | 2.56 | 2.56 |
| 356.39 | 2.89 | 2.89 |