Basic Information
ID: ALA3586822
Type: Binding
Description: Inhibition of Sprague-Dawley rat brain microsomal FAAH using N-(2-hydroxyethyl)-4-pyren-1-ylbutanamide as substrate assessed as 4-pyren-1-ylbutanoic acid release preincubated for 10 mins with substrate followed by protein addition measured after 60 mins by reverse phase HPLC with fluorescence detection method
Format: BAO_0000019
Organism: Rattus norvegicus
Strain: Sprague-Dawley
Tissue: Brain
Subcellular Fraction: Microsomal
Target: Anandamide amidohydrolase(ALA3229)
Document: ALA3585341
Inhibition of Sprague-Dawley rat brain microsomal FAAH using N-(2-hydroxyethyl)-4-pyren-1-ylbutanamide as substrate assessed as 4-pyren-1-ylbutanoic acid release preincubated for 10 mins with substrate followed by protein addition measured after 60 mins by reverse phase HPLC with fluorescence detection method: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3586822
IC50
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 294.35 | 4.21 | 4.21 |
| 338.41 | 3.87 | 3.87 |
| 453.59 | 6.87 | 6.87 |
| 452.60 | 7.48 | 7.48 |
| 424.54 | 6.70 | 6.70 |
| 510.63 | 7.27 | 7.27 |
| 494.64 | 7.68 | 7.68 |
| 477.61 | 7.35 | 7.35 |
| 452.60 | 7.48 | 7.48 |
| 376.50 | 5.81 | 5.81 |
| 488.63 | 8.32 | 8.32 |
| 412.53 | 6.66 | 6.66 |
| 412.53 | 6.66 | 6.66 |
| 336.44 | 4.99 | 4.99 |
| 337.42 | 4.39 | 4.39 |
| 338.41 | 3.78 | 3.78 |
| 337.42 | 4.39 | 4.39 |
| 308.38 | 4.21 | 4.21 |
| 322.41 | 4.60 | 4.60 |
| 350.46 | 5.38 | 5.38 |
| 364.49 | 5.77 | 5.77 |
| 323.40 | 4.00 | 4.00 |
| 337.42 | 4.39 | 4.39 |