In vivo inhibition of mTORC1 in human PC3 cells xenografted in mouse assessed as inhibition of Akt phosphorylation at S473 at 100 mg/kg, po measured a...

Basic Information

ID: ALA3587381

Type: Functional

Description: In vivo inhibition of mTORC1 in human PC3 cells xenografted in mouse assessed as inhibition of Akt phosphorylation at S473 at 100 mg/kg, po measured after 2 hrs relative to control

Format: BAO_0000218

Organism: Mus musculus

Cell type: PC-3

Target: Mus musculus(ALA375)

Document: ALA3585315

In vivo inhibition of mTORC1 in human PC3 cells xenografted in mouse assessed as inhibition of Akt phosphorylation at S473 at 100 mg/kg, po measured after 2 hrs relative to control: 1

Associated Items: Associated Bioactivities Associated Compounds

Activity Charts

Bioactivity

Activity Types for Assay ALA3587381

Inhibition

Total(9)

Parent Molecular Weight	ALogP	Polar Surface Area
383.45	1.95	1.95
397.48	2.34	2.34
397.48	2.34	2.34
343.39	1.17	1.17
383.45	1.95	1.95
411.51	2.73	2.73
397.48	2.48	2.48
397.48	2.48	2.48
397.48	2.48	2.48

Parent Molecular Weight

ALogP

Polar Surface Area

383.45

1.95

397.48

2.34

397.48

2.34

343.39

1.17

383.45

1.95

411.51

2.73

397.48

2.48

397.48

2.48

397.48

2.48

In vivo inhibition of mTORC1 in human PC3 cells xenografted in mouse assessed as inhibition of Akt phosphorylation at S473 at 100 mg/kg, po measured a...

Basic Information

Activity Charts

Compound Summary