Basic Information
ID: ALA3587386
Type: Unassigned
Description: Ratio of drug uptake in human PC3 cells xenografted in mouse at 100 mg/kg, po measured after 4 hrs to IC50 for mTORC1 in human PC3 cells assessed as inhibition of S6 phosphorylation
Format: BAO_0000218
Organism: Homo sapiens
Cell type: PC-3
Target: PC-3(ALA390)
Document: ALA3585315
Ratio of drug uptake in human PC3 cells xenografted in mouse at 100 mg/kg, po measured after 4 hrs to IC50 for mTORC1 in human PC3 cells assessed as inhibition of S6 phosphorylation: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3587386
Ratio
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 383.45 | 1.95 | 1.95 |
| 397.48 | 2.34 | 2.34 |
| 397.48 | 2.34 | 2.34 |
| 343.39 | 1.17 | 1.17 |
| 383.45 | 1.95 | 1.95 |
| 411.51 | 2.73 | 2.73 |
| 397.48 | 2.48 | 2.48 |
| 397.48 | 2.48 | 2.48 |
| 397.48 | 2.48 | 2.48 |