Antagonist activity at human recombinant NOP receptor expressed in CHO cells co-expressing C-terminally modifed Gaqi5 protein assessed as inhibition o...

Basic Information

ID: ALA3587627

Type: Functional

Description: Antagonist activity at human recombinant NOP receptor expressed in CHO cells co-expressing C-terminally modifed Gaqi5 protein assessed as inhibition of agonist response up to 10 uM by Fluo-4AM dye based calcium mobilization assay

Format: BAO_0000219

Organism: Homo sapiens

Cell type: CHO

Target:  Nociceptin receptor(ALA2014)

Document:  ALA3585322

Antagonist activity at human recombinant NOP receptor expressed in CHO cells co-expressing C-terminally modifed Gaqi5 protein assessed as inhibition of agonist response up to 10 uM by Fluo-4AM dye based calcium mobilization assay: 1

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
536.633.403.40
550.663.793.79
522.603.063.06