Basic Information
ID: ALA3587629
Type: Functional
Description: Antagonist activity at human recombinant NOP receptor expressed in CHO cells co-expressing C-terminally modifed Gaqi5 protein assessed as inhibition of (S)-8-(Chroman-4-yl)-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one-induced response by Fluo-4AM dye based calcium mobilization assay
Format: BAO_0000219
Organism: Homo sapiens
Cell type: CHO
Target: Nociceptin receptor(ALA2014)
Document: ALA3585322
Antagonist activity at human recombinant NOP receptor expressed in CHO cells co-expressing C-terminally modifed Gaqi5 protein assessed as inhibition of (S)-8-(Chroman-4-yl)-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one-induced response by Fluo-4AM dye based calcium mobilization assay: 1
Activity Charts
Bioactivity
Activity Types for Assay ALA3587629
pKb
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 418.41 | 6.17 | 6.17 |