Assay Report Card

Basic Information

ID: ALA3588664

Type: Functional

Description: Mutation read through activity in african green monkey COS7 cells transfected with dual-reporter plasmid encoding beta-galactosidase and luciferase genes connected with TGA-containing mouse mdx gene exon 23 nucleotide sequence as premature termination codon assessed as ratio of luciferase activity to beta-galactosidase activity at 200 uM incubated for 48 hrs at 37 degC relative to basal level

Organism: Chlorocebus aethiops

Cell type: COS-7

Activity Charts

Compound Summary

Parent Molecular WeightALogPPolar Surface Area
248.28-2.54-2.54
496.56-5.61-5.61
232.28-1.51-1.51
246.31-1.12-1.12
218.26-1.90-1.90
204.23-2.29-2.29
232.28-1.51-1.51
218.26-1.90-1.90
204.23-2.29-2.29
190.20-2.68-2.68
246.31-1.42-1.42
308.38-0.24-0.24
245.33-1.85-1.85
307.40-0.67-0.67
387.280.520.52
387.280.520.52
387.280.520.52
342.830.410.41
342.830.410.41
342.830.410.41
353.38-0.33-0.33
353.38-0.33-0.33
353.38-0.33-0.33
338.41-0.23-0.23
338.41-0.23-0.23
338.41-0.23-0.23