Basic Information
ID: ALA3590860
Type: Binding
Description: Displacement of [3H]DTG from sigma2 receptor in Sprague-Dawley rat liver membranes incubated for 2 hrs in presence of dextrallorphan by liquid scintillation counting based competitive radioligand binding assay
Organism: Rattus norvegicus
Strain: Sprague-Dawley
Tissue: Liver
Subcellular Fraction: Membrane
Activity Charts
Bioactivity
Activity Types for Assay ALA3590860
Ki
Compound Summary
| Parent Molecular Weight | ALogP | Polar Surface Area |
|---|---|---|
| 259.39 | 3.17 | 3.17 |
| 307.44 | 3.39 | 3.39 |
| 322.45 | 2.98 | 2.98 |
| 257.38 | 2.95 | 2.95 |
| 353.44 | 3.25 | 3.25 |
| 305.39 | 3.02 | 3.02 |
| 369.48 | 3.74 | 3.74 |
| 384.50 | 3.90 | 3.90 |
| 383.51 | 4.50 | 4.50 |
| 384.50 | 3.45 | 3.45 |
| 381.49 | 4.41 | 4.41 |
| 385.52 | 4.58 | 4.58 |
| 399.51 | 3.61 | 3.61 |
| 425.54 | 4.25 | 4.25 |
| 459.61 | 5.71 | 5.71 |
| 397.53 | 4.58 | 4.58 |
| 355.45 | 3.68 | 3.68 |
| 390.54 | 3.57 | 3.57 |
| 429.51 | 4.36 | 4.36 |
| 384.50 | 3.90 | 3.90 |
| 335.46 | 3.52 | 3.52 |
| 335.46 | 3.52 | 3.52 |
| 308.43 | 2.34 | 2.34 |
| 305.42 | 3.30 | 3.30 |
| 323.44 | 2.50 | 2.50 |
| 321.46 | 3.47 | 3.47 |
| 314.47 | 2.47 | 2.47 |
| 308.43 | 2.79 | 2.79 |
| 322.45 | 2.98 | 2.98 |
| 444.55 | 4.79 | 4.79 |
| 458.58 | 4.86 | 4.86 |
| 444.55 | 4.79 | 4.79 |
| 458.58 | 4.86 | 4.86 |
| 275.39 | 2.27 | 2.27 |
| 301.43 | 2.91 | 2.91 |
| 335.49 | 4.37 | 4.37 |
| 273.42 | 3.24 | 3.24 |
| 231.34 | 2.35 | 2.35 |
| 266.43 | 2.24 | 2.24 |
| 260.38 | 2.56 | 2.56 |
| 383.51 | 4.50 | 4.50 |
| 384.50 | 3.45 | 3.45 |
| 381.49 | 4.41 | 4.41 |
| 385.52 | 4.58 | 4.58 |
| 399.51 | 3.61 | 3.61 |
| 425.54 | 4.25 | 4.25 |
| 459.61 | 5.71 | 5.71 |
| 397.53 | 4.58 | 4.58 |
| 355.45 | 3.68 | 3.68 |
| 390.54 | 3.57 | 3.57 |
| 429.51 | 4.36 | 4.36 |
| 260.38 | 2.11 | 2.11 |
| 257.38 | 3.08 | 3.08 |
| 261.41 | 3.24 | 3.24 |